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It is in the culture of orthopaedics that steroids have adverse effects on joints and when used in the presence of a bacterial infection, steroids can lead to chronic symptoms; such as swelling of the bone (osteolysis) and inflammation of the joints. The incidence and duration of osteolysis varies from one patient to the next. However, most cases of osteolysis in adult patients with arthritic joints develop in individuals with prior steroid use. Some patients will develop chronic osteolysis with the use of steroids as a result of a previous steroid infection; however, this does not invariably happen. In adults and children, the most common underlying cause of osteolysis is infection of the joints. Infection may be from an infectious agent, such as a virus or bacteria, which may attach to and enter the joint capsule, or infection directly from the environment. In children, such as athletes, there is evidence that infection by pathogens may accelerate the development of osteolysis and may be the cause of some cases of joint inflammation. In some instances both inflammatory and cartilage destruction can occur simultaneously. In other instances, these two phenomena may happen simultaneously. In a case of joint inflammation, the inflammation may be the result of a factor that may cause the pain and inflammation. In children, swelling of the joint capsules may play a role in the inflammation and may be the result of the inflammation, followed by an increase in cartilage destruction. In these instances, it is not always possible to determine the cause of osteolysis in that it is difficult to determine whether bone damage was the underlying factor. Steroid use may promote the development of some types of chronic joint damage. In addition, steroid use may have a role in osteoarthritis. In children, steroid use may cause an increase in the incidence of osteoarthritis. In adults, both steroids and osteoarthritis may increase the incidence of osteoarthritis. The extent to which steroids influence the development of joint damage (acute, chronic, or both) will be reflected by the level of pain. Joint pain may be a predictor of the development of chronic joint damage. A study conducted in the 1960s found that osteoarthritis is associated with the use of oral steroids that are not recommended for children because they are "controllable and reversible"; however, children who develop osteoarthritis may require an oral steroid that is not recommended for adults. The effects of steroid use on the development of hip and hip joint cartilage destruction in adults are not well understood and there has been no study to date on the effect of steroid use on the Similar articles:

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